Genomic Risk Predictionbased on Poligenic Risk Score
Allelica is the first and only company to offer a Software as a Service to perform Genomic Risk Prediction based on Polygenic Risk Score. This method summarizes the contribution of hundreds to Millions of genetic variants in determining the risk of developing multifactorial diseases. Polygenic Risk Scores are developed thanks to the availability of scientific studies based on tens of thousands of individuals, published only in recent years in high impact factor journals. Furthermore, the availability of large datasets, such as the UK Biobank with more than 500,000 volunteers, accelerated at an unprecedented rate the research on Personal Genomics, allowing the validation of the predictive algorithms. Allelica does not consider genetic risk individually, but also integrates clinical factors and lifestyle models. This approach guarantees the maximum level of personalization and effectiveness of the results provided. Allelica pipeline accepts any genome-wide array data, performs quality controls and imputes missing data.
Diabetes Type 1:
Irritable Bowel Syndrome:
Diabetes type 2: