Tag: brca

Disease is Polygenic

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January 23 2020

In the late 19th Century, a Moravian monk named Gregor Mendel passed his time by running experiments cross-breeding different types of pea plant.

Amongst his botanical collection of perennials he had legumes with a variety of physical characteristics. He had short and tall pea plants, pea plants with different coloured flowers, and plants with different types of leaf and pea shape.

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The UK Biobank: unleashing the power of the genome.

blogbrcabreastcancercardiologygenomicpredictiongenomicshealthcarepolygenicriskscoreprevention

January 15 2020

A central goal of preventative medicine is to identify the people most at risk of disease early enough that something can be done. Spotting those at higher risk of getting cancer, for example, means that screening programs can be targeted at this group, allowing the disease to be caught early and dealt with whilst it’s relatively cheap and the cancer is small. As we learn more about the drivers of many diseases, from breast cancer to cardiovascular disease, understanding the combination of factors that contribute to the development of disease will provide information that will help people reduce their risk through lifestyle change and therapeutics.

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